Zepbound® is the brand name for the drug Tirzepatide when doctors prescribe it for weight loss. Zepbound® helps many people lose a dramatic amount of weight. It may also help reduce other health problems associated with excess weight.
What is Zepbound®?
Zepbound® is an injectable prescription medicine that may help adults with obesity, or with excess weight (overweight) who also have weight-related medical problems, lose weight and keep it off. Zepbound® should be used with a reduced-calorie diet and increased physical activity.
How Do You Take Zepbound®? Is It a Pill?
No. Zepbound® is not a pill. It’s an injectable medication that patients need to use once a week. It comes in three doses: 5, 10 and 15 milligrams.
How Much Weight Do People Lose with Zepbound®?
During clinical trials, study volunteers who used tirzepatide lost as much as 21% of their body weight.
The average weight loss for study subjects who did not have diabetes and used the largest dose of Zepbound® (15 milligrams, once a week) was 18%, according to the FDA.
People who have diabetes tend to lose less weight with these new drugs than those who don’t have diabetes. Another study found that people with diabetes who used Zepbound® lost an average of 12% of their body weight, FDA officials said.
Are Zepbound® & Semaglutide® All the Same?
No. Zepbound® (also known as tirzepatide) works a little differently than Semaglutides.
Zepbound®, and all other Semaglutides® Mounjaro, Wegovy, Saxenda, and Ozempic) work in similar ways to reduce appetite. But Zepbound® is what’s called “dual-agonist” drug while Wegovy, Saxenda, and Ozempic are what’s known as “single-agonist” drugs. These drugs activate important hormone pathways in the body.
Tirzepatide is in a completely new drug class. It’s a combination peptide. This dual agonist approach seems to cause people who use Zepbound® injections to lose even more weight than those who use a medication that only activates one hormone pathway.”
These drugs stimulate hormones that help control blood sugar levels and reduce appetite, triggering weight loss. The hormones are glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP).
Semaglutides® activate the GLP-1 pathway, while Zepbound® activate two: both GLP-1 and GIP.
